| Gene Symbol | ECSIT |
| Full Name | Evolutionarily Conserved Signaling Intermediate in Toll Pathways |
| Chromosome | 19q13.32 |
| Protein Type | Adaptor Protein |
| Primary Expression | microglia and astrocytes, where it regulates [neuroinflammatory responses](/mechani |
| Molecular Weight | 46 kDa |
| Amino Acids | 410 aa |
| Exons | 11 |
| Pathways | NF-κB |
| UniProt ID | [Q9BS26](https://www.uniprot.org/uniprot/Q9BS26) |
| Ensembl ID | ENSG00000136999 |
| OMIM | 607373 |
| GeneCards | ECSIT |
| Human Protein Atlas | ECSIT |
| Exon 1 | Encodes the 5' UTR and N-terminal region containing the mitochondrial targeting sequence |
| Associated Diseases | neurodegeneration |
| Interactions | AND, AUTOPHAGY, BECN1, CANCER, CHUK, IKBKB |
| KG Connections | 52 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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