gene 986 words KG: HTRA1
Contents

HTRA1 Gene

🧬 Gene Info
Gene SymbolHTRA1
Full NameHTRA1 serine peptidase 1
Chromosome10q26.13
Protein FamilyHTRA serine protease family
Protein TypeProtease
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight53 kDa
Amino Acids480 aa
Exons6
PathwaysTGF-β
UniProt IDQ92743
NCBI Gene ID5657
Ensembl IDENSG00000166033
OMIM607784
GeneCardsHTRA1
Human Protein AtlasHTRA1
Associated Diseasesneurodegeneration
InteractionsAND, APOE, GENETIC LOCI, Proteins, Ras, VEGFA
KG Connections32 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Piezoelectric Nanochannel BBB Disruption
Score: 0.52

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

Notch and Gamma-Secretase Modulators for Parkinson's Di
company · KG edge: contributes_to
Diseases Overview
disease · KG edge: contributes_to
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: expressed_in
Genes
index · KG edge: contributes_to
COL4A1 Gene
gene · KG edge: contributes_to

Knowledge Graph (12 edges)

NOTCH3 contributes_to HTRA1
HTRA1 contributes_to COL4A1
HTRA1 contributes_to OVERVIEW
HTRA1 associated_with APOE
APOE interacts_with HTRA1
APOE associated_with HTRA1
HTRA1 contributes_to NOTCH3
HTRA1 regulates VEGFA
HTRA1 activates VEGFA
GENES contributes_to HTRA1

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