| Gene Symbol | BNIP3 |
| Full Name | BCL2 Interacting Protein 3 |
| Chromosome | 10q26.3 |
| Function | is a pro-apoptotic BH3-only protein that plays a dual role in regulating both apoptosis and mitophagy. |
| Primary Expression | Ubiquitous; high expression in brain, heart, and skeletal muscle |
| Pathways | Apoptosis, Autophagy, Chaperone, Histone Modification, Lipid Metabolism |
| UniProt ID | Q12986 |
| NCBI Gene ID | 664 |
| Ensembl ID | ENSG00000176171 |
| OMIM | 604488 |
| GeneCards | BNIP3 |
| Human Protein Atlas | BNIP3 |
| Associated Diseases | AD, ALI, Als, Alzheimer, brain ischemia |
| Known Drugs/Compounds | dimethyl fumarate |
| Interactions | ABCD3, ACETYL-COA, Actin, ADORA2A, AGING, ALS |
| KG Connections | 1257 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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