cell 674 words KG: GABA
Contents

GABA Transporter (GAT) Neurons

🧫 Cell Type Info
Cell TypeGABA
Key PathwaysGABAergic Signaling
Associated DiseasesALS, Als, Alzheimer, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis, Ataxia
Related GenesATG, GABA, GABARAP, HDAC3, LC3, MTOR
Linked Hypotheses398 hypotheses

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

Wikipedia

Related Hypotheses (44)

APOE-Dependent Autophagy Restoration
Score: 0.88
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65
TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62
Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.92
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.78
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78
SASP-Mediated Cholinergic Synapse Disruption
Score: 0.76
Circadian Clock-Autophagy Synchronization
Score: 0.76
Multi-Modal Stress Response Harmonization
Score: 0.76
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
Senescent Cell Mitochondrial DNA Release
Score: 0.74
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
Adenosine-Astrocyte Metabolic Reset
Score: 0.73
Phase-Separated Organelle Targeting
Score: 0.73
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Proteostasis Enhancement via APOE Chaperone Targeting
Score: 0.72
pg 1/3Next →

Related Analyses (23)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived

Related Experiments (10)

Non-Dopaminergic Neurotransmitter Degeneration in PD - Exper
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Metabolic Pathway-Targeted Therapy in ALS
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90

See Also (7)

acetylcholine
general · KG edge: co_discussed
ACTB Gene
gene · KG edge: activates
adra2b Gene
gene · KG edge: expressed_in
AKT1 Gene
gene · KG edge: interacts_with
Gene Page: ALS4 (SENATAXIN)
gene · KG edge: activates

Knowledge Graph (12 edges)

GABA associated_with MTOR
GABA associated_with TFEB
AKT associated_with GABA
BACE1 associated_with GABA
TAU associated_with GABA
GABA associated_with neuroinflammation
GABA associated_with serotonin
GABA associated_with GABAergic neurons
GABA interacts_with GABARAP
FLCN interacts_with GABA

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.