| Gene Symbol | SNAP25 |
| Full Name | Synaptosomal-Associated Protein 25 |
| Aliases | SNAP25 gene page |
| Chromosome | 20p12.3 |
| Protein Family | SNAP-25 family (t-SNARE) |
| Protein Type | Structural Protein |
| Target Class | Structural Protein |
| Function | Priming – SNARE proteins assemble partially |
| Mechanism of Action | Protein cleavage by botulinum toxin or small molecule modulators of SNARE complex formation |
| Druggability | Low (0.33) |
| Clinical Stage | Approved |
| Molecular Weight | 25 kDa |
| Amino Acids | 206 aa |
| Pathways | Complement, Endocytosis, Exocytosis, Long-Term Potentiation, Synaptic Vesicle Tau Capture Inhibition |
| UniProt ID | P60880 |
| NCBI Gene ID | 6616 |
| Ensembl ID | ENSG00000132639 |
| OMIM | 600240 |
| GeneCards | SNAP25 |
| Human Protein Atlas | SNAP25 |
| Associated Diseases | Als, Alzheimer, Alzheimer's Disease, Amyotrophic Lateral Sclerosis |
| Known Drugs/Compounds | rapamycin, RAPAMYCIN |
| Interactions | ACTB, ACTG1, Actin, AD, AKT, ALZHEIMER |
| SciDEX Target | View Target Profile (2 clinical trials) |
| SciDEX Hypotheses | Targeting Synaptic Vesicle Release Machinery to Bl Synaptic Vesicle Tau Capture Inhibition Synaptic Vesicle Tau Capture Inhibition |
| KG Connections | 655 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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