gene 524 words KG: TGFBR1
Contents

TGFBR1 — TGF-beta Receptor 1

🧬 Gene Info
Gene SymbolTGFBR1
Full NameTGF-beta Receptor 1
Chromosome9q22
Protein TypeReceptor
FunctionTGFBR1 encodes the Type I TGF-beta receptor, a serine/threonine protein kinase that mediates the signaling of transforming growth factor-beta (TGF-β) family cytokines.
Amino Acids567 aa
PathwaysTGF-β, TGF-β signaling
UniProt IDP36897
NCBI Gene ID7046
Ensembl IDENSG00000106799
OMIM190181
GeneCardsTGFBR1
Human Protein AtlasTGFBR1
Extracellular domainLigand binding
Transmembrane domainSingle pass
Associated DiseasesAls, Cancer, Carcinoma, epilepsy, Ms, Tumor
InteractionsACVR1, AKT, BMP4, BMP7, CBL, CDC42
SciDEX HypothesesEarly Postnatal TGF-beta Signaling Establishes Lif
KG Connections93 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

TGF-β1–SMAD2/3 Axis as Master Suppressor of Microglial Train
Score: 0.71
Early Postnatal TGF-beta Signaling Establishes Lifelong Regi
Score: 0.50

Knowledge Graph (12 edges)

TGFBR2 associated_with TGFBR1
BMP4 activates TGFBR1
MYC associated_with TGFBR1
E2F5 associated_with TGFBR1
CDKN2B associated_with TGFBR1
TGFBR1 associated_with BMP2
TGFBR1 activates TGFB2
TGFBR1 activates BMP7
PIK3CA associated_with TGFBR1
CDK6 associated_with TGFBR1

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