| Gene Symbol | NOS3 |
| Full Name | Endothelial Nitric Oxide Synthase (NOS3) |
| Aliases | Nitric Oxide Synthase 3 |
| Chromosome | 7q36 |
| Protein Type | Protein |
| Function | This is the basis for the therapeutic use of nitrates in cardiovascular disease [@katusic2009]. |
| Primary Expression | vascular endothelial cells where it catalyzes the production of nitric oxide (NO) from L-arginine |
| Amino Acids | 490 aa |
| Pathways | Mapk, autophagy pathway, complement cascade, phagocytosis |
| UniProt ID | Search UniProt |
| GeneCards | NOS3 |
| Human Protein Atlas | NOS3 |
| Associated Diseases | ALS, Alzheimer, Cancer, podocyte foot process effacement |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACOX1, ADAMTS1, Adiponectin, ADIPOQ, AMPK, ATG |
| KG Connections | 379 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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