| Gene Symbol | MAPK1 |
| Chromosome | 22q11.2 |
| Protein Family | MAP kinase family, CMGC group |
| Protein Type | Kinase |
| Function | is a protein involved in various cellular processes relevant to neurodegeneration. |
| Subcellular Localization | Cytoplasm, nucleus |
| Molecular Weight | 41 kDa |
| Amino Acids | 360 aa |
| Pathways | MAPK, Mapk, MAPK signaling, MAPK pathway |
| UniProt ID | P28482 |
| GeneCards | MAPK1 |
| Human Protein Atlas | MAPK1 |
| MAPK3 (ERK1) | Paralogous kinase with overlapping but distinct functions |
| MEK1/MEK2 | Upstream activating kinases |
| RAF proteins | Further upstream components of the cascade |
| Associated Diseases | Aging, Als, Alzheimer, Cancer, Carcinoma |
| Known Drugs/Compounds | Chrysotoxine, DEP, DMP, DOP, Zuojin Pill |
| Interactions | ACTB, ACTG1, Actin, ACVR1, AIFM1, AKT |
| KG Connections | 889 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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