| Gene Symbol | IBA1 |
| Full Name | Ionized Calcium-Binding Adapter Molecule 1 |
| Function | is a protein encoded by the AIF1 gene that ### Microglial Marker |
| Molecular Weight | 17.0 kDa |
| Amino Acids | 147 aa |
| Pathways | Mapk |
| UniProt ID | [P55008](https://www.uniprot.org/uniprotkb/P55008) |
| GeneCards | IBA1 |
| Human Protein Atlas | IBA1 |
| Actin bundling | Crosslinks actin filaments into bundles |
| Membrane ruffling | Required for formation of membrane ruffles and lamellipodia |
| Motility | Essential for microglial migration and chemotaxis |
| Phagocytosis | Participates in phagocytic cup formation |
| Antigen presentation | Associated with MHC class II expression |
| Inflammatory signaling | Modulates cytokine production |
| Associated Diseases | AD, Aging, Als, Alzheimer, Alzheimer's disease |
| Known Drugs/Compounds | rapamycin |
| Interactions | AB, ACTB, AD, ADAM10, AGING, AIF1 |
| KG Connections | 1090 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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