Contents

IBA1 Protein

🔬 Protein Info

Gene Symbol	IBA1
Full Name	Ionized Calcium-Binding Adapter Molecule 1
Function	is a protein encoded by the AIF1 gene that ### Microglial Marker
Molecular Weight	17.0 kDa
Amino Acids	147 aa
Pathways	Mapk
UniProt ID	[P55008](https://www.uniprot.org/uniprotkb/P55008)
GeneCards	IBA1
Human Protein Atlas	IBA1
Actin bundling	Crosslinks actin filaments into bundles
Membrane ruffling	Required for formation of membrane ruffles and lamellipodia
Motility	Essential for microglial migration and chemotaxis
Phagocytosis	Participates in phagocytic cup formation
Antigen presentation	Associated with MHC class II expression
Inflammatory signaling	Modulates cytokine production
Associated Diseases	AD, Aging, Als, Alzheimer, Alzheimer's disease
Known Drugs/Compounds	rapamycin
Interactions	AB, ACTB, AD, ADAM10, AGING, AIF1
KG Connections	1089 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING