| Gene Symbol | GRIN1 |
| Chromosome | 9q34.1 |
| Protein Type | Protein |
| Function | of 938 amino acids |
| Molecular Weight | 105 kDa |
| Amino Acids | 938 aa |
| Exons | 21 |
| Pathways | SRC-mediated Phosphorylation |
| UniProt ID | Search UniProt |
| GeneCards | GRIN1 |
| Human Protein Atlas | GRIN1 |
| Extracellular domain | Two lobes (S1 and S2) forming the agonist binding domain |
| Transmembrane domain | Four helices (M1-M4) forming the ion channel pore |
| C-terminal domain | Intracellular tail for signaling interactions |
| Glycine/D-serine binding site | NR1 subunit binds the co-agonist |
| Associated Diseases | Huntington's disease, Memory Impairment |
| Known Drugs/Compounds | D-glutamate |
| Interactions | ADRA1A, ADRA1B, DRD1, DRD2, GRIA1, HCRTR1 |
| KG Connections | 58 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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