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gene 2,946 words KG: GRIN1
Contents

GRIN1 — NMDA Receptor Subunit 1

🧬 Gene Info
Gene SymbolGRIN1
Chromosome9q34.1
Protein TypeProtein
Functionof 938 amino acids
Molecular Weight105 kDa
Amino Acids938 aa
Exons21
PathwaysSRC-mediated Phosphorylation
UniProt IDSearch UniProt
GeneCardsGRIN1
Human Protein AtlasGRIN1
Associated DiseasesHuntington's disease, Memory Impairment
Known Drugs/CompoundsD-glutamate
InteractionsADRA1A, ADRA1B, DRD1, DRD2, GRIA1, HCRTR1
KG Connections58 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.87Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.86Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72Circadian Glymphatic Rescue Therapy (Melatonin-focused)
Score: 0.71Orexin-Microglia Modulation Therapy
Score: 0.71Hypocretin-Neurogenesis Coupling Therapy
Score: 0.69Trinucleotide Repeat Sequestration via CRISPR-Guided RNA Tar
Score: 0.61Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedPerivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · archivedCRISPR-based therapeutic approaches for neurodegenerative di
neurodegeneration · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_inApoptosis in Neurodegeneration
entity · KG edge: therapeutic_targetAstrocytes
entity · KG edge: expressed_inDNA Methylation
entity · KG edge: activatesEpigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: activates

Knowledge Graph (12 edges)

DRD2 activates GRIN1
HRH3 activates GRIN1
HCRTR2 activates GRIN1
ADRA1B activates GRIN1
DRD1 activates GRIN1
GRIA1 activates GRIN1
ADRA1A activates GRIN1
HRH1 activates GRIN1
GRIN1 activates HCRTR1
CAPN1 therapeutic_target GRIN1

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