| Gene Symbol | ABCD3 |
| Chromosome | 1p22.1 |
| Protein Family | ABC transporter subfamily D |
| Protein Type | Transporter |
| Function | ABCD3 functions as a peroxisomal membrane transporter |
| Primary Expression | multiple tissues, with highest levels in liver, kidney, and brain |
| Subcellular Localization | Peroxisomal membrane |
| Molecular Weight | 79.7 kDa |
| Pathways | Tgf-Beta, Wnt |
| UniProt ID | [O75323](https://www.uniprot.org/uniprot/O75323) |
| GeneCards | ABCD3 |
| Human Protein Atlas | ABCD3 |
| Nucleotide-binding domain (NBD) | Two NBDs containing Walker A (P-loop) and Walker B motifs |
| ABC signature (C-loop) | Consensus sequence specific to ABC transporters |
| Transmembrane domains | Six alpha-helical transmembrane segments |
| Associated Diseases | AD, ALI, Als, Alzheimer, Cancer |
| Interactions | ABCD1, ABCD2, Actin, ALS, ALZHEIMER, ALZHEIMER DISEASE |
| KG Connections | 470 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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