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index 475 words KG: GENES
Contents

Genes

🔬 Protein Info
Gene SymbolGENES
PathwaysAdaptive Immunity, Akt, Ampk Signaling, Amyloid, Angiogenesis
GeneCardsGENES
Human Protein AtlasGENES
Associated DiseasesAging, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Interactions6-OHDA, A2M, ABCA1, ABCA7, ABCB1, ABCG1
KG Connections7700 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

Wikipedia

Related Hypotheses (190)

Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70Mitochondrial Transfer Pathway Enhancement
Score: 0.70Complement C1q Mimetic Decoy Therapy
Score: 0.69Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69Ocular Immune Privilege Extension
Score: 0.69Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69Extracellular Matrix Stiffness Modulation
Score: 0.69Ganglioside Rebalancing Therapy
Score: 0.69Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69Lysosomal Positioning Dynamics Modulation
Score: 0.69CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68Flotillin-1 Stabilization Compounds
Score: 0.68R-Loop Resolution Enhancement Therapy
Score: 0.68Osmotic Gradient Restoration via Selective AQP1 Enhancement
Score: 0.68Oligodendrocyte Protectin D1 Mimetic for Myelin Resolution
Score: 0.68Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.67RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.67
← Prevpg 6/10Next →

Related Analyses (27)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completedSEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · completedWhich cell types show the most significant expression change
neurodegeneration · completed

Related Experiments (28)

TREM2 Agonist Therapy for Parkinson's Disease — Experimental
validation · proposed · Score: 0.45TREM2 Function in Alzheimer's Disease — From Risk Variant to
validation · proposed · Score: 0.45Microglial TREM2 Agonist In Vivo Efficacy
validation · proposed · Score: 0.45Axonal Transport Dysfunction Validation in Parkinson's Disea
clinical · proposed · Score: 0.40s:** - Single-cell RNA-seq to measure editing efficiency acr
falsification · proposed · Score: 0.40

See Also (15)

OSK Reprogramming and Yamanaka Factors in Neurodegenera
mechanism · Pages share 6 hypothesesABCA2 Gene - ATP Binding Cassette Subfamily A Member 2
gene · KG edge: transportsABCA1 - ATP-Binding Cassette Transporter A1
gene · KG edge: interacts_withABCG1 Gene
gene · KG edge: associated_withABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

MIRNAS regulates GENES
GENES regulates APOPTOSIS
GENES regulates DIFFERENTIATION
GENES interacts_with RICTOR
GENES interacts_with HSP70
GENES interacts_with PPARG
GENES interacts_with RHEB
GENES interacts_with CALCOCO2
GENES interacts_with MAVS
GENES interacts_with RIPK1

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