gene 3,104 words KG: TEAD1
Contents

TEAD1 — TEA Domain Transcription Factor 1

🧬 Gene Info
Gene SymbolTEAD1
Full NameTEA Domain Transcription Factor 1
Chromosome11p15.4
Protein TypeTranscription Factor
Functionis a member of the TEA domain (TEA/ATTS) transcription factor family.
Amino Acids426 aa
Exons16
UniProt IDP28347
NCBI Gene ID7003
Ensembl IDENSG00000187091
OMIM189892
GeneCardsTEAD1
Human Protein AtlasTEAD1
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsActin, BLM, MITOCHONDRIAL DYSFUNCTION, PRDX3, Ras, Rb
KG Connections30 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (7)

Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.77
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed

Related Experiments (2)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (11)

Neurodegeneration
disease · KG edge: implicated_in
Genes
index · KG edge: therapeutic_target
BLM — Bloom Syndrome Protein
gene · KG edge: inhibits
CDK4 Gene
gene · KG edge: therapeutic_target
EGFR — Epidermal Growth Factor Receptor
gene · KG edge: regulates

Knowledge Graph (12 edges)

CDK4 therapeutic_target TEAD1
TEAD1 regulates EGFR
TEAD1 therapeutic_target FGFR3
TEAD1 therapeutic_target NF1
TEAD1 therapeutic_target IDH1
EGFR regulates TEAD1
IDH1 therapeutic_target TEAD1
NF1 therapeutic_target TEAD1
FGFR3 therapeutic_target TEAD1
BLM inhibits TEAD1

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