| Gene Symbol | SIRT5 |
| Full Name | Sirtuin 5 |
| Aliases | Page for SIRT5 Protein |
| Chromosome | 6p23 |
| Protein Family | Sirtuin family (class I) |
| Function | is a member of the sirtuin family of NAD⁺-dependent protein deacylases that is primarily localized to mitochondria. |
| Subcellular Localization | mitochondria. Unlike other sirtuins, SIRT5 possesses unique enzymatic activities including desuccinylation, demalonylati |
| Molecular Weight | 34 kDa |
| Amino Acids | 310 aa |
| Pathways | Glutamine Metabolism, Glycolysis, Mitophagy, Oxidative Stress, Unfolded Protein Response |
| UniProt ID | Q9NXE1 |
| NCBI Gene ID | 83737 |
| Ensembl ID | ENSG00000124587 |
| OMIM | 604603 |
| GeneCards | SIRT5 |
| Human Protein Atlas | SIRT5 |
| Associated Diseases | Als, Alzheimer, cancer |
| Known Drugs/Compounds | Mc3482, MC3482 |
| Interactions | AGING, AKT2, ALZHEIMER, ALZHEIMER'S DISEASE, AND, App |
| KG Connections | 214 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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