| Gene Symbol | S100A8 |
| Full Name | S100 Calcium Binding Protein A8 |
| Chromosome | 1q21.3 |
| Protein Family | S100 calcium-binding protein family |
| Function | S100A8 and the S100A8/A9 complex (calprotectin) have several critical functions |
| Primary Expression | specific cell types and pathological conditions |
| Molecular Weight | 10.8 kDa |
| Amino Acids | 93 aa |
| Exons | 3 |
| Pathways | NF-κB, MAPK signaling |
| GeneCards | S100A8 |
| Human Protein Atlas | S100A8 |
| N-terminal hinge region | Low complexity region involved in protein interactions |
| EF-hand I (pseudo) | Non-functional calcium-binding site at N-terminus |
| EF-hand II (canonical) | Functional calcium-binding site at C-terminus |
| Associated Diseases | Alzheimer, Cancer, Heart Failure, Lupus, Ms, Sepsis |
| Known Drugs/Compounds | GW201 |
| Interactions | ACE2, Actin, AGING, AMPK, AND, APOPTOSIS |
| KG Connections | 293 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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