gene 874 words KG: RGS4
Contents

RGS4 Gene

🧬 Gene Info
Gene SymbolRGS4
Chromosome1q23.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionPrefrontal cortex, Striatum, Hippocampus
Molecular Weight24 kDa
Amino Acids206 aa
PathwaysAmyloid, Apoptosis, Oxidative Stress
UniProt IDP49798
NCBI Gene ID5999
Ensembl IDENSG00000117408
OMIM602514
GeneCardsRGS4
Human Protein AtlasRGS4
Associated DiseasesAls, Bipolar, Depression, Ms, Schizophrenia
InteractionsAKT, BACE1, CNR1, DAO, DISC1, G72
KG Connections127 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
TREM2-mediated microglial tau clearance enhancement
Score: 0.62

Related Analyses (4)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Bipolar Cells in Visual Processing
cell · KG edge: associated_with
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: expressed_in
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
Genes
index · KG edge: associated_with
BDNF Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

HTR2A associated_with RGS4
DISC1 associated_with RGS4
FKBP5 associated_with RGS4
NRG1 associated_with RGS4
DAO associated_with RGS4
BMAL1 associated_with RGS4
GRM4 associated_with RGS4
SYNGR1 associated_with RGS4
BDNF associated_with RGS4
NCAM1 associated_with RGS4

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