gene 1,361 words KG: HTR2A
Contents

HTR2A Gene

🧬 Gene Info
Gene SymbolHTR2A
Full Name5-Hydroxytryptamine Receptor 2A
Chromosome13q14.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionCortex, Platelets, Smooth muscle, Olfactory bulb
Molecular Weight60 kDa
UniProt IDP28223
NCBI Gene ID3352
Ensembl IDENSG00000102468
GeneCardsHTR2A
Human Protein AtlasHTR2A
Extracellular N-terminusContains glycosylation sites important for receptor folding and trafficking
Associated DiseasesAls, Alzheimer, Autism, Bipolar, Cancer
InteractionsCACNA1B, CACNA1H, DRD1, DRD2, GABRA1, GABRB2
KG Connections155 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
APOE-Dependent Autophagy Restoration
Score: 0.85
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Cerebellum
brain · KG edge: expressed_in
Bipolar Cells in Visual Processing
cell · KG edge: associated_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
BDNF Gene
gene · KG edge: associated_with
BMAL1 (ARNTL) Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

HTR2A associated_with DISC1
HTR2A associated_with FKBP5
HTR2A associated_with NRG1
HTR2A associated_with DAO
HTR2A associated_with BMAL1
HTR2A associated_with GRM4
HTR2A associated_with SYNGR1
HTR2A associated_with BDNF
HTR2A associated_with NCAM1
HTR2A associated_with RGS4

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