gene 2,239 words KG: GABRA5
Contents

GABRA5 Gene

🧬 Gene Info
Gene SymbolGABRA5
Full NameGamma-Aminobutyric Acid Type A Receptor Alpha5 Subunit
Chromosome15q12
Protein TypeReceptor
Functionencodes a 456-amino acid protein that forms the distinctive pentameric structure of the GABA-A receptor.
Subcellular Localizationextrasynaptic locations in the hippocampus and cortex, making them uniquely positioned to modulate neuronal excitability
Molecular Weight52 kDa
Amino Acids456 aa
Exons9
UniProt IDP31644
NCBI Gene ID2568
Ensembl IDENSG00000118190
OMIM137142
GeneCardsGABRA5
Human Protein AtlasGABRA5
Associated DiseasesAls, Bipolar, Depression, Ms, Schizophrenia
InteractionsGABRA1, GABRG2, TRPM2
KG Connections73 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (7)

Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
HCN1-Mediated Resonance Frequency Stabilization Therapy
Score: 0.65

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Bipolar Cells in Visual Processing
cell · KG edge: associated_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: associated_with
Genes
index · KG edge: associated_with
BDNF Gene
gene · KG edge: associated_with
BMAL1 (ARNTL) Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

HTR2A associated_with GABRA5
DISC1 associated_with GABRA5
FKBP5 associated_with GABRA5
NRG1 associated_with GABRA5
DAO associated_with GABRA5
BMAL1 associated_with GABRA5
GRM4 associated_with GABRA5
SYNGR1 associated_with GABRA5
BDNF associated_with GABRA5
NCAM1 associated_with GABRA5

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