gene 511 words KG: RAD51
Contents

RAD51

🧬 Gene Info
Gene SymbolRAD51
Full NameRAD51 Recombinase
Chromosome15q15.1
FunctionRAD51 is a recombinase protein essential for homologous recombination (HR) repair of double-strand DNA breaks.
Primary Expressionall brain regions, with particularly high expression in dopaminergic neurons of the substantia nigra, motor cortex, and hippo
Molecular Weight37 kDa
Amino Acids339 aa
PathwaysHomologous Recombination
UniProt IDP43251
NCBI Gene ID5888
Ensembl IDENSG00000102009
OMIM179520
GeneCardsRAD51
Human Protein AtlasRAD51
Associated Diseasesneurodegeneration
InteractionsAND, ATM, ATR, BRCA1, CANCER, DNA
KG Connections69 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (5)

Stress Granule Phase Separation Modulators
Score: 0.72
Axonal RNA Transport Reconstitution
Score: 0.70
Extracellular Matrix Stiffness Modulation
Score: 0.69
RNA Granule Nucleation Site Modulation
Score: 0.66
VCP-Mediated Autophagy Enhancement
Score: 0.57

Related Analyses (4)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: activates
Ferroptosis Validation in Parkinson's Disease
experiment · KG edge: activates
ATM Gene
gene · KG edge: activates
ATR Gene
gene · KG edge: activates
BRCA1 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

RAD54 activates RAD51
VCP activates RAD51
RAD51 activates ATR
RAD51 activates ATM
ATM activates RAD51
ATR activates RAD51
RAD51 activates RAD54
RAD51 activates VCP
BRCA1 activates RAD51
ATM regulates RAD51

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