gene 553 words KG: PILRB
Contents

PILRB Gene

🧬 Gene Info
Gene SymbolPILRB
Chromosome7q22.1.
Protein TypeReceptor
Functionencodes a membrane protein involved in immune cell signaling.
Primary Expressionimmune cells:
Molecular Weight29 kDa
Amino Acids264 aa
PathwaysPI3K, MAPK pathway
UniProt IDQ9Y5U4
NCBI Gene ID29998
GeneCardsPILRB
Human Protein AtlasPILRB
Associated DiseasesAlzheimer, Dementia, Ms
InteractionsABCA7, APOE, BIN1, CD33, LRRK2, PILRA
KG Connections34 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
TREM2-mediated microglial tau clearance enhancement
Score: 0.62

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (10)

Neurodegeneration
disease · KG edge: implicated_in
GBA (Redirect)
redirect · KG edge: associated_with
IL6 (Redirect)
redirect · KG edge: associated_with
TREM2 Protein (Triggering Receptor Expressed on Myeloid
entity · KG edge: associated_with
CR1 Gene — Complement Component 1q Receptor
gene · KG edge: associated_with

Knowledge Graph (12 edges)

CR2 associated_with PILRB
TREM2 associated_with PILRB
IL6 associated_with PILRB
ZCWPW1 associated_with PILRB
CTSH associated_with PILRB
PILRB associated_with GBA
PILRB associated_with CR1
CD33 interacts_with PILRB
LRRK2 interacts_with PILRB
PILRB interacts_with RGS1

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