gene 727 words KG: NPAS2
Contents

NPAS2 Gene

🧬 Gene Info
Gene SymbolNPAS2
Full NameNeuronal PAS Domain Protein 2
Chromosome2q22.1
FunctionThe NPAS2 gene encodes Neuronal PAS Domain Protein 2, a transcription factor that serves as a core component of the mammalian circadian clock.
Molecular Weight87 kDa
PathwaysCBFs
UniProt IDQ8BZD0
NCBI Gene ID10327
Ensembl IDENSG00000107077
OMIM605504
GeneCardsNPAS2
Human Protein AtlasNPAS2
Associated DiseasesFreezing Tolerance
InteractionsBMAL1, MTNR1A, MTNR1B, PER1, PER2
KG Connections38 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (12)

Circadian Clock-Autophagy Synchronization
Score: 0.76
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Purinergic Signaling Polarization Control
Score: 0.71
Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.70
Microglial Purinergic Reprogramming
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Temporal Decoupling via Circadian Clock Reset
Score: 0.54
Optogenetic Control of Mitochondrial Transfer Networks
Score: 0.48
Gap Junction Hemichannel Modulation for Controlled Mitochond
Score: 0.36

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Proposed experiment from debate on Astrocytes adopt A1 (neur
falsification · proposed · Score: 0.40

See Also (9)

Genes
index · KG edge: expressed_in
ARNTL Gene — Aryl Hydrocarbon Receptor Nuclear Transloc
gene · KG edge: expressed_in
BMAL1 (ARNTL) Gene
gene · KG edge: associated_with
CLOCK Gene
gene · KG edge: associated_with
CRY1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

NPAS2 interacts_with BMAL1
PER3 associated_with NPAS2
PER1 associated_with NPAS2
CRY1 associated_with NPAS2
NPAS2 associated_with CRY2
NPAS2 associated_with PER2
NPAS2 associated_with CLOCK
NPAS2 associated_with BMAL1
NPAS2 interacts_with HOS1
NPAS2 participates_in CBFs

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.