gene 805 words KG: PER3
Contents

PER3 Gene

🧬 Gene Info
Gene SymbolPER3
Full NamePeriod Circadian Regulator 3
Chromosome1p36.23
FunctionThe PER3 gene encodes the Period Circadian Regulator 3 protein, a core component of the mammalian circadian clock.
Molecular Weight121 kDa
Pathwaysubiquitin-proteasome
UniProt IDQ8WY51
NCBI Gene ID8863
Ensembl IDENSG00000149257
OMIM604352
GeneCardsPER3
Human Protein AtlasPER3
Associated DiseasesALS, autism spectrum disorder
InteractionsHCRTR2, PER2
KG Connections55 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (9)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
Circadian Clock-Autophagy Synchronization
Score: 0.76
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (14)

Apoptosis in Neurodegeneration
entity · KG edge: expressed_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: expressed_in
Genes
index · KG edge: expressed_in
ARNTL Gene — Aryl Hydrocarbon Receptor Nuclear Transloc
gene · KG edge: expressed_in
BMAL1 (ARNTL) Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PER3 expressed_in PER1
PER3 expressed_in CRY1
PER3 expressed_in CRY2
PER3 expressed_in PER2
PER3 expressed_in SIRT1
PER3 expressed_in CLOCK
PER3 associated_with PER1
PER3 associated_with CRY1
PER3 associated_with NPAS2
PER3 associated_with CRY2

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