gene 588 words KG: NDUFS1
Contents

NDUFS1 Gene

🧬 Gene Info
Gene SymbolNDUFS1
FunctionThe NDUFS1 gene encodes NDUFS1 Protein, a protein involved in various cellular processes relevant to neuronal function and survival.
Primary Expressionvarious brain regions, with notable expression in: - Cerebral cortex - Hippocampus - Basal gang
PathwaysOxidative Phosphorylation, Oxidative Stress
Ensembl IDENSG00000156510
GeneCardsNDUFS1
Human Protein AtlasNDUFS1
Associated DiseasesParkinson
InteractionsACO2, ATP, COX15, COX4I1, COX7A1, COX8A
KG Connections77 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (12)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (9)

ATP P2X3 Receptor Neurons
cell · KG edge: therapeutic_target
Genes
index · KG edge: activates
ACO2 — Aconitase 2
gene · KG edge: therapeutic_target
CYCS
gene · KG edge: activates
GLUD1 - Glutamate Dehydrogenase 1
gene · KG edge: causes

Knowledge Graph (12 edges)

VDAC1 therapeutic_target NDUFS1
HSPA9 therapeutic_target NDUFS1
CYCS therapeutic_target NDUFS1
ACO2 therapeutic_target NDUFS1
GLUD1 associated_with NDUFS1
SNCA therapeutic_target NDUFS1
LRPPRC associated_with NDUFS1
NDUFS2 associated_with NDUFS1
NDUFS1 therapeutic_target SDHA
NDUFS1 therapeutic_target CYCS

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