gene

COX7A1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about COX7A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

11Connections

0Hypotheses

0Analyses

7Outgoing

4Incoming

0Experiments

0Debates

Summary

Page for COX7A1 - Cytochrome C Oxidase Subunit

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🧬 Gene Info

Gene Symbol	COX7A1
Full Name	Cytochrome C Oxidase Subunit VIIa Polypeptide 1
Aliases	Page for COX7A1
Chromosome	19q13.12
Function	COX7A1 encodes a subunit of cytochrome c oxidase (Complex IV) of the mitochondrial respiratory chain.
Primary Expression	skeletal muscle and heart tissue
UniProt ID	P24310
NCBI Gene ID	997
Ensembl ID	ENSG00000127838
GeneCards	COX7A1
Human Protein Atlas	COX7A1
Associated Diseases	neurodegeneration
Interactions	COX15, COX4I1, COX8A, NDUFA12, NDUFA5, NDUFS1
KG Connections	11 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: COX7A1 — AlphaFold P24310 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

COX7A1 - Cytochrome C Oxidase Subunit

gene · 685 words

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Pathway Diagram

flowchart TD
    N0["COX7A1"]
    N1["COX8A"]
    N0 -->|"co expressed with"| N1
    N2["NDUFA12"]
    N0 -->|"co expressed with"| N2
    N3["COX15"]
    N3 -->|"co expressed with"| N0
    N4["COX4I1"]
    N4 -->|"co expressed with"| N0
    N5["neurodegeneration"]
    N0 -->|"implicated in"| N5

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 gene
    class N2 gene
    class N3 protein
    class N4 gene

Outgoing (7)

Target	Relation	Type	Str
COX8A	inhibits	gene	0.60
NDUFA12	inhibits	gene	0.60
NDUFA5	inhibits	gene	0.60
NDUFS1	inhibits	gene	0.60
NDUFS4	inhibits	gene	0.60
COX8A	co_expressed_with	gene	0.50
NDUFA12	co_expressed_with	gene	0.50

Incoming (4)

Source	Relation	Type	Str
COX15	inhibits	gene	0.60
COX4I1	inhibits	gene	0.60
COX15	co_expressed_with	protein	0.50
COX4I1	co_expressed_with	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning COX7A1 in their description or question text

No additional research found