gene 661 words KG: MS4A4E
Contents

MS4A4E Gene - Membrane-Spanning 4-Domains A4E

🧬 Gene Info
Gene SymbolMS4A4E
Full NameMembrane-Spanning 4-Domains A4E
AliasesPage for MS4A4E Gene
Chromosome11q12.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionBrain, Spleen, Lymphocytes, Monocytes
UniProt IDQ9NRL3
NCBI Gene ID245722
Ensembl IDENSG00000166908
GeneCardsMS4A4E
Human Protein AtlasMS4A4E
Associated DiseasesAlzheimer
InteractionsABCA7, APOE, BIN1, CD2AP, CLU, CR1
KG Connections40 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Membrane Cholesterol Gradient Modulators
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Membrane Repair Enhancement
Score: 0.54

Related Analyses (4)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (13)

ABCA7 (Redirect)
redirect · KG edge: interacts_with
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: associated_with
Genes
index · KG edge: interacts_with
BIN1 — Bridging Integrator 1
gene · KG edge: interacts_with
CD2AP Gene — CD2-Associated Protein
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

ZCWPW1 interacts_with MS4A4E
GAB2 interacts_with MS4A4E
CR1 interacts_with MS4A4E
MS4A6A interacts_with MS4A4E
ABCA7 interacts_with MS4A4E
PICALM interacts_with MS4A4E
MS4A4E interacts_with CLU
MS4A4E interacts_with APOE
MS4A4E interacts_with BIN1
MS4A4E interacts_with CD2AP

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