| Gene Symbol | IL2 |
| Chromosome | 4q26 |
| Protein Type | Cytokine |
| Function | IL-2 has essential and complex functions: |
| Molecular Weight | 15 kDa |
| Pathways | PI3K, MAPK |
| NCBI Gene ID | 3559 |
| GeneCards | IL2 |
| Human Protein Atlas | IL2 |
| T cell proliferation | Primary cytokine driving activated T cell expansion[@malek2011] |
| Treg development | Essential for regulatory T cell (Treg) maintenance and function |
| NK cell activation | Enhances NK cell cytotoxicity and proliferation |
| Immune tolerance | Central to self-tolerance via Treg maintenance |
| Neurodevelopment | Influences neural precursor cell proliferation and differentiation |
| Synaptic plasticity | IL-2 receptor expression in hippocampus suggests roles in learning and memory |
| Associated Diseases | neurodegeneration |
| Interactions | AKT, AKT1, MYC, PDGFR, VEGFA |
| KG Connections | 27 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
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