| Gene Symbol | IGF1 |
| Chromosome | 12q23.2 |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 7.6 kDa |
| Amino Acids | 70 aa |
| Exons | 6 |
| Pathways | PI3K, MAPK |
| Ensembl ID | ENSG00000117471 |
| GeneCards | IGF1 |
| Human Protein Atlas | IGF1 |
| Class 1 transcripts | Include exon 1, encode the classic IGF-1A and IGF-1B isoforms |
| Class 2 transcripts | Include exon 2, produce variants with different N-terminal signal peptides |
| Ea isoform | The predominant brain isoform |
| Eb isoform | Less abundant, alternative splicing |
| Associated Diseases | ALS, Alzheimer, Ms |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACHE, AGING, AKT, AKT1, ALZHEIMER, AMPK |
| KG Connections | 528 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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