gene 748 words KG: APOA1
Contents

APOA1 Gene

🧬 Gene Info
Gene SymbolAPOA1
Full NameApolipoprotein A1
ChromosomeChr11q23.3
FunctionThe APOA1 gene encodes Apolipoprotein A1, the primary protein component of high-density lipoprotein (HDL) particles.
UniProt IDP02647
NCBI Gene ID335
Ensembl IDENSG00000118137
OMIM107680
GeneCardsAPOA1
Human Protein AtlasAPOA1
Associated DiseasesAD, Als, Alzheimer, AMI, ARM
Interactions4E-BP1, ABCA1, abca2, ABCA2, ABCG1, ACTB
KG Connections295 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (27)

APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74
APOE Isoform Conversion Therapy
Score: 0.72
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
CYP46A1 Overexpression Gene Therapy
Score: 0.92
APOE-Dependent Autophagy Restoration
Score: 0.85

Related Analyses (4)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Actin Cytoskeleton Dynamics in Neurodegeneration
mechanism · KG edge: co_discussed
ABCA2 Gene - ATP Binding Cassette Subfamily A Member 2
gene · KG edge: activates
ABCG1 Gene
gene · KG edge: interacts_with
ACTB Gene
gene · KG edge: interacts_with
Alzheimer Indonesia
institution · KG edge: degrades

Knowledge Graph (12 edges)

ACTB interacts_with APOA1
P2RY12 inhibits APOA1
APOA1 interacts_with ULK1
APOA1 interacts_with ATG5
APOA1 interacts_with EIF4EBP1
APOA1 interacts_with LC3
APOA1 inhibits MTOR
APOA1 interacts_with ABCG1
APOA1 interacts_with SQSTM1
APOA1 interacts_with ABCA1

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