| Gene Symbol | GPNMB |
| Full Name | Glycoprotein Nmb |
| Chromosome | 7p15.3 |
| Function | GPNMB is a type I transmembrane protein with an extracellular domain containing a polycystic kidney disease (PKD) domain and a车位 ITAM-like motif. |
| Primary Expression | various tissues including brain, bone, and immune cells |
| Molecular Weight | 63.5 kDa |
| Amino Acids | 572 aa |
| Pathways | Autophagy, Cholesterol, Immune Response, Inflammatory Pathways |
| UniProt ID | Q14990 |
| NCBI Gene ID | 2690 |
| Ensembl ID | ENSG00000136235 |
| GeneCards | GPNMB |
| Human Protein Atlas | GPNMB |
| APOE | Interacts with immune responses GPNMB influences |
| Microglia | Primary central nervous system source of GPNMB |
| Associated Diseases | AD, ALI, Als, Alzheimer, Alzheimer's disease |
| Interactions | Actin, Adiponectin, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AMYLOID-BETA |
| KG Connections | 425 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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