| Gene Symbol | GADD34 |
| Aliases | Growth Arrest and DNA Damage Inducible Protein 34 / PPP1R15A |
| Chromosome | 19q13.12 |
| Protein Type | Phosphatase |
| Function | encodes a stress-induced regulatory subunit of protein phosphatase 1 (PP1) that plays a critical role in the integrated stress response (ISR). |
| Molecular Weight | 81 kDa |
| Amino Acids | 674 aa |
| Pathways | Apoptosis, Er Stress, Unfolded Protein Response |
| Ensembl ID | ENSG00000175319 |
| GeneCards | GADD34 |
| Human Protein Atlas | GADD34 |
| PP1 binding | The RVxF motif mediates binding to PP1 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | ATF4, ATF6, DDIT3, ERN1, GENES, PERK |
| KG Connections | 19 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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