gene 1,282 words KG: FASN
Contents

FASN Gene

🧬 Gene Info
Gene SymbolFASN
Chromosome1q25
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight273 kDa
PathwaysAkt, Lipid Metabolism, Mtor, Pi3K
Ensembl IDENSG00000169710
GeneCardsFASN
Human Protein AtlasFASN
Associated DiseasesAD, Aging, AMI, ARM, Atherosclerosis, breast cancer
InteractionsABCA1, ACACA, ACC, ACLY, ACOX1, ACSL4
KG Connections352 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (24)

Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.67
Arginine Methylation Enhancement Therapy
Score: 0.65
Oligodendrocyte White Matter Vulnerability
Score: 0.65
Temporal Decoupling via Circadian Clock Reset
Score: 0.54
← Prevpg 2/2

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Proposed experiment from debate on Microglia activate astroc
falsification · completed · Score: 0.40

See Also (15)

ALOX15 - Arachidonate 15-Lipoxygenase
gene · KG edge: inhibits
Accelerating Medicines Partnership for Alzheimer's Dise
institution · KG edge: implicated_in
Apoptosis in Neurodegeneration
entity · KG edge: activates
ALDH2 — Aldehyde Dehydrogenase 2
gene · KG edge: activates
Alzheimer Indonesia
institution · KG edge: expressed_in

Knowledge Graph (12 edges)

PRMT1 activates FASN
FASN activates SRC
FASN activates HK1
FASN activates MTOR
FASN activates PTEN
FASN activates HK2
FASN inhibits BAX
FASN inhibits ALOX15
FASN inhibits GSDMD
FASN inhibits SCD1

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