| Gene Symbol | CCR6 |
| Chromosome | 6q27 |
| Protein Type | Receptor |
| Function | encodes a G protein-coupled receptor for CCL20 (MIP-3α/MIP-3a), also known as exodus-1 or LARC (Liver and Activation-Regulated Chemokine). |
| Primary Expression | rheumatoid synovium |
| Amino Acids | 374 aa |
| Exons | 4 |
| Ensembl ID | ENSG00000112486 |
| GeneCards | CCR6 |
| Human Protein Atlas | CCR6 |
| N-terminal extracellular domain | Ligand binding |
| Seven transmembrane domains | GPCR core |
| Three extracellular loops | Ligand interaction |
| Three intracellular loops | Signal transduction |
| C-terminal intracellular tail | G protein coupling and desensitization |
| Associated Diseases | neurodegeneration |
| Interactions | AND, APOE, CANCER, CCL20, CD163, CD4 |
| KG Connections | 30 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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