gene 519 words KG: BECLIN1
Contents

BECN1 Gene

🧬 Gene Info
Gene SymbolBECLIN1
Full NameBECN1
Protein TypeGene
Functionis a gene/protein encoding a key neuronal protein involved in synaptic function, signal transduction, and cellular homeostasis
PathwaysApoptosis, Autophagy, Mtor, Oxidative Stress
GeneCardsBECLIN1
Human Protein AtlasBECLIN1
Associated DiseasesAls, Alzheimer, Cancer, Colorectal Cancer, Glioblastoma, Inflammation
InteractionsABCA1, ACTB, ADSL, AKT, AKT1, ALZHEIMER
KG Connections618 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (23)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.78
Circadian Clock-Autophagy Synchronization
Score: 0.76
Circadian-Synchronized Proteostasis Enhancement
Score: 0.74
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56
APOE-Dependent Autophagy Restoration
Score: 0.89
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
CYP46A1 Overexpression Gene Therapy
Score: 0.77
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration
Score: 0.70
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.68
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
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Related Analyses (9)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (15)

AMBRA1 Gene
gene · KG edge: activates
ADRB2 Gene
gene · KG edge: therapeutic_target
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: inhibits
AKT1 Gene
gene · KG edge: activates
Alzheimer Indonesia
institution · KG edge: associated_with

Knowledge Graph (12 edges)

CHOP regulates BECLIN1
FIS1 associated_with BECLIN1
VEGF associated_with BECLIN1
BAX associated_with BECLIN1
TRAF6 associated_with BECLIN1
CHOP associated_with BECLIN1
NRF2 associated_with BECLIN1
MTOR associated_with BECLIN1
BECLIN1 associated_with BCL2
BECLIN1 associated_with TAAR1

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