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gene 1,339 words KG: AGGF1
Contents

AGGF1 Gene - Angiogenic Factor

🧬 Gene Info
Gene SymbolAGGF1
AliasesPage for AGGF1 Gene
Chromosome5q13.2
FunctionAGGF1 has several important molecular functions
Primary ExpressionEndothelial Cells, Brain, Heart, Lung
UniProt IDQ9Y5K8
NCBI Gene ID55109
Ensembl IDENSG00000100985
OMIM609589
GeneCardsAGGF1
Human Protein AtlasAGGF1
InteractionsAKT, PERK, VEGFA
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (6)

Ephrin-B2/EphB4 Axis Manipulation
Score: 0.64CYP46A1 Overexpression Gene Therapy
Score: 0.92Retinal Vascular Microcirculation Rescue
Score: 0.72Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.71Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (10)

Neurodegeneration
disease · KG edge: implicated_inDAB2 — Disabled Clathrin Adaptor Protein
gene · KG edge: upregulatesEPHB4 Gene
gene · KG edge: upregulatesGATA1 - GATA Binding Protein 1
gene · KG edge: upregulatesHIF1A Gene - Hypoxia Inducible Factor 1 Subunit Alpha
gene · KG edge: upregulates

Knowledge Graph (12 edges)

AGGF1 activates VEGFA
AGGF1 upregulates EPHB4
AGGF1 upregulates DAB2
AGGF1 activates AKT
AGGF1 inhibits PERK
AGGF1 upregulates TNFSF12
AGGF1 binds ITGA7
AGGF1 stabilizes TP53
AGGF1 upregulates MCL1
AGGF1 upregulates FLT4

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