gene 913 words KG: GATA1
Contents

GATA1 - GATA Binding Protein 1

🧬 Gene Info
Gene SymbolGATA1
Full NameGATA Binding Protein 1
AliasesPage for GATA1
FunctionGATA1 belongs to the GATA family of transcription factors characterized by conserved zinc finger domains that bind the DNA sequence (A/T)GATA(A/G).
PathwaysApoptosis, Cell Cycle
Ensembl IDENSG00000102145
GeneCardsGATA1
Human Protein AtlasGATA1
Associated Diseasesneurodegeneration
InteractionsAPOPTOSIS, CANCER, CREBBP, GATA2, GENES, HSP70
KG Connections31 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (6)

Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Extracellular Matrix Stiffness Modulation
Score: 0.69
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
LRP1-Dependent Tau Uptake Disruption
Score: 0.60
Blood-Brain Barrier SPM Shuttle System
Score: 0.53

Related Analyses (7)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

Neurodegeneration
disease · KG edge: implicated_in
Apoptosis in Neurodegeneration
entity · KG edge: interacts_with
Tumor Necrosis Factor (TNF)
entity · KG edge: interacts_with
AGGF1 Gene - Angiogenic Factor
gene · KG edge: upregulates
CREBBP Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

SNCA contributes_to GATA1
GATA1 activates HSP70
LRP1 interacts_with GATA1
NR3C1 interacts_with GATA1
GATA1 interacts_with MYC
GATA1 interacts_with CREBBP
GATA1 interacts_with IL6ST
IL6ST interacts_with GATA1
MYC interacts_with GATA1
GATA1 interacts_with NR3C1

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