concept

STATINS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about STATINS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

66Connections

0Hypotheses

0Analyses

50Outgoing

0Incoming

0Experiments

0Debates

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💡 Concept Info

Name	STATINS

Pathway Diagram

graph TD
    STATINS[STATINS]
    STATINS -->|activates| LDLR[LDLR]
    STATINS -->|inhibits| HMGCR[HMGCR]
    STATINS -->|regulates| autophagy[autophagy]
    STATINS -->|inhibits| LAMP2[LAMP2]
    STATINS -->|inhibits| MMP9[MMP9]
    STATINS -->|activates| LDL[LDL]
    STATINS -->|treats| Alzheimer_s_disease[Alzheimer's disease]
    STATINS -->|modulates| unfolded_protein_response[unfolded protein response]
    STATINS -->|activates| ABCA1[ABCA1]

Outgoing (66)

Target	Relation	Type	Str
HMGCR	inhibits	gene	0.90
LDLR	activates	protein	0.90
HMGCR	activates	gene	0.80
unfolded protein response	modulates	pathway	0.70
LAMP2	inhibits	protein	0.70
autophagy	regulates	process	0.70
MMP9	inhibits	protein	0.70
Alzheimer's disease	treats	disease	0.70
LDL	activates	gene	0.70
MAP1LC3	activates	gene	0.60
AMPK	activates	gene	0.60
ALS	treats	disease	0.60
ATP	interacts_with	gene	0.60
MAP1LC3	interacts_with	gene	0.60
LDL	interacts_with	gene	0.60
AMPK	interacts_with	gene	0.60
synaptic plasticity	modulates	pathway	0.60
MAPK signaling	modulates	pathway	0.60
multiple sclerosis	treats	disease	0.60
Parkinson's disease	treats	disease	0.60
ROS	activates	gene	0.60
ATP	activates	gene	0.60
ROS	inhibits	gene	0.60
ABCA1	activates	gene	0.60
P2RY12	activates	gene	0.60
LOX	activates	gene	0.60
ULK1	activates	gene	0.60
ACTB	activates	gene	0.60
SQSTM1	activates	gene	0.60
LC3	activates	gene	0.60
ATG5	activates	gene	0.60
AMPK signaling	modulates	pathway	0.60
ABCA1	interacts_with	gene	0.60
P2RY12	interacts_with	gene	0.60
LOX	interacts_with	gene	0.60
ULK1	interacts_with	gene	0.60
ACTB	interacts_with	gene	0.60
SQSTM1	interacts_with	gene	0.60
LC3	interacts_with	gene	0.60
ATG5	interacts_with	gene	0.60
GPX4	activates	gene	0.60
ferroptosis	modulates	pathway	0.60
GPX4	inhibits	gene	0.60
LDL	inhibits	gene	0.60
LDL	treats	gene	0.60
spinal muscular atrophy	treats	disease	0.60
LDL	associated_with	gene	0.60
LDL	metabolizes	gene	0.60
BDNF	activates	gene	0.60
BDNF	treats	gene	0.60

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity