Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GALT: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GALT |
| Key Genes/Proteins | Akt, AKT, AND, APOPTOSIS, ATM, AUTOPHAGY |
| Related Diseases | Als, ALS, classic galactosemia, Classic Galactosemia |
| Related Pathways | Apoptosis, Autophagy |
Knowledge base pages for this entity
graph TD
GALT["GALT"]
GALT -->|"causes"| Classic_Galactosemia["Classic Galactosemia"]
GALT -->|"causes"| classic_galactosemia["classic galactosemia"]
GALT -->|"activates"| ALS["ALS"]
GALT -->|"activates"| Als["Als"]
GALT -->|"activates"| PI3K["PI3K"]
GALT -->|"activates"| Oxidative_Stress["Oxidative Stress"]
GALT -->|"activates"| Pi3K_Akt["Pi3K/Akt"]
GALT -->|"activates"| Apoptosis["Apoptosis"]
GENES["GENES"] -->|"activates"| GALT
DNA["DNA"] -->|"activates"| GALT
AKT["AKT"] -->|"activates"| GALT
ATM["ATM"] -->|"activates"| GALT
CASP9["CASP9"] -->|"activates"| GALT
AUTOPHAGY["AUTOPHAGY"] -->|"activates"| GALT
OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"activates"| GALT
PTEN["PTEN"] -->|"activates"| GALT| Target | Relation | Type | Str |
|---|---|---|---|
| classic galactosemia | causes | disease | 0.95 |
| Classic Galactosemia | causes | disease | 0.95 |
| ALS | activates | disease | 0.65 |
| Als | activates | disease | 0.65 |
| Pi3K/Akt | activates | pathway | 0.60 |
| Apoptosis | activates | pathway | 0.60 |
| Autophagy | activates | pathway | 0.60 |
| GENES | activates | gene | 0.60 |
| ATM | activates | gene | 0.60 |
| DNA | activates | gene | 0.60 |
| RNA | activates | gene | 0.60 |
| APOPTOSIS | activates | gene | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| PTEN | activates | gene | 0.60 |
| CASP9 | activates | gene | 0.60 |
| Akt | activates | protein | 0.60 |
| PI3K | activates | gene | 0.60 |
| Oxidative Stress | activates | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GENES | activates | gene | 0.60 |
| DNA | activates | gene | 0.60 |
| AKT | activates | gene | 0.60 |
| ATM | activates | gene | 0.60 |
| CASP9 | activates | gene | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| OXIDATIVE STRESS | activates | gene | 0.60 |
| PTEN | activates | gene | 0.60 |
| RNA | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| APOPTOSIS | activates | gene | 0.60 |
| EIF2A | activates | gene | 0.60 |
| PI3K | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GALT in their description or question text
No additional research found