gene 2,283 words KG: CASP3
Contents

CASP3 Gene

🧬 Gene Info
Gene SymbolCASP3
Full NameCaspase 3
Chromosome4q34
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight20 kDa
Amino Acids277 aa
PathwaysAkt, Apoptosis, Autophagy, Epigenetic, Glycolysis
UniProt ID[P42574](https://www.uniprot.org/uniprot/P42574)
Ensembl IDENSG00000164305
GeneCardsCASP3
Human Protein AtlasCASP3
Associated DiseasesAging, Als, Alzheimer, Alzheimer_disease, Alzheimer's disease
Known Drugs/CompoundsANTHOCYANINS, aristolochic_acids, Atbc, berberine, BERBERINE, Bpmc
InteractionsABP, ACHE, ACTB, AKT, AKT1, AKT1S1
KG Connections1489 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (2)

Apoptosis-Senescence Decision Point Intervention
Score: 0.65
Caspase-2/3-mediated D421 truncation generates disease-speci
Score: 0.46

Knowledge Graph (12 edges)

CASP3 encodes CASPASE3
OPTN interacts_with CASP3
CASP3 regulates AKT1
CASP3 regulates CALCOCO2
CASP3 regulates CGAS
CASP3 regulates CFTR
CASP3 interacts_with SQSTM1
CASP3 interacts_with RPS6KB1
CASP3 interacts_with GRB2
CASP3 interacts_with RHEB

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