concept

ANK3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ANK3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

50Connections

0Hypotheses

0Analyses

33Outgoing

17Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ANK3
Key Genes/Proteins	AND, CACNA1G, CAMK4, CANCER, CD8, ETV6
Related Diseases	Autism, Bipolar, Cancer, Ms

Wiki Pages (3)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    ANK3["ANK3"]
    ANK3 -->|"inhibits"| Bipolar["Bipolar"]
    ANK3 -->|"target for"| Ms["Ms"]
    ANK3 -->|"target for"| Cancer["Cancer"]
    ANK3 -->|"target for"| Tumor["Tumor"]
    ANK3 -->|"inhibits"| Schizophrenia["Schizophrenia"]
    ANK3 -->|"inhibits"| Autism["Autism"]
    ANK3 -->|"activates"| ZBTB20["ZBTB20"]
    ANK3 -->|"activates"| ETV6["ETV6"]
    ETV6 -->|"activates"| ANK3
    CAMK4["CAMK4"] -->|"activates"| ANK3
    GENES["GENES"] -->|"activates"| ANK3
    ZBTB20 -->|"activates"| ANK3
    SETD1A["SETD1A"] -->|"inhibits"| ANK3
    KMT2A["KMT2A"] -->|"inhibits"| ANK3
    SHANK3["SHANK3"] -->|"inhibits"| ANK3

Outgoing (33)

Target	Relation	Type	Str
Cancer	therapeutic_target	disease	0.65
Tumor	therapeutic_target	disease	0.65
Bipolar	inhibits	disease	0.65
Ms	therapeutic_target	disease	0.65
Schizophrenia	inhibits	disease	0.65
Autism	inhibits	disease	0.65
Tumor	associated_with	disease	0.65
Cancer	associated_with	disease	0.65
GENES	activates	gene	0.60
CANCER	associated_with	gene	0.60
ubiquitin-proteasome	participates_in	pathway	0.60
RNA	associated_with	gene	0.60
AND	activates	gene	0.60
T Cell	associated_with	cell_type	0.60
GAIN	expressed_in	gene	0.60
RNA	expressed_in	gene	0.60
KMT2B	inhibits	gene	0.60
SHANK3	inhibits	gene	0.60
KMT2D	inhibits	gene	0.60
CACNA1G	inhibits	gene	0.60
KMT2A	inhibits	gene	0.60
AND	inhibits	gene	0.60
Ras	inhibits	protein	0.60
SETD1A	inhibits	gene	0.60
ZBTB20	activates	gene	0.60
ETV6	activates	gene	0.60
CAMK4	activates	gene	0.60
SPP1	associated_with	gene	0.60
CD8	therapeutic_target	gene	0.60
SPP1	therapeutic_target	gene	0.60
CD8	associated_with	gene	0.60
TEX	expressed_in	cell_type	0.56
T Cell	expressed_in	cell_type	0.55

Incoming (17)

Source	Relation	Type	Str
SETD1A	inhibits	gene	0.60
SPP1	associated_with	gene	0.60
CD8	associated_with	gene	0.60
ETV6	activates	gene	0.60
CAMK4	activates	gene	0.60
GENES	activates	gene	0.60
ZBTB20	activates	gene	0.60
RNA	associated_with	gene	0.60
CANCER	associated_with	gene	0.60
KMT2A	inhibits	gene	0.60
SHANK3	inhibits	gene	0.60
GENES	inhibits	gene	0.60
CACNA1G	inhibits	gene	0.60
KMT2B	inhibits	gene	0.60
GAIN	expressed_in	gene	0.60
KMT2D	inhibits	gene	0.60
RNA	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ANK3 in their description or question text

No additional research found