Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ZBTB20: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ZBTB20 |
| Key Genes/Proteins | AND, ANK3, CAMK4, CANCER, CD8, ETV6 |
| Related Diseases | Cancer, stroke |
| Related Pathways | mitochondrial function, oxidative stress response |
graph TD
ZBTB20["ZBTB20"]
ZBTB20 -->|"target for"| Cancer["Cancer"]
ZBTB20 -->|"target for"| Tumor["Tumor"]
ZBTB20 -->|"activates"| ETV6["ETV6"]
ZBTB20 -->|"activates"| CAMK4["CAMK4"]
ZBTB20 -->|"activates"| ANK3["ANK3"]
ZBTB20 -->|"activates"| GENES["GENES"]
ZBTB20 -->|"activates"| AND["AND"]
ZBTB20 -->|"expressed in"| TEX["TEX"]
ANK3 -->|"activates"| ZBTB20
ETV6 -->|"activates"| ZBTB20
CAMK4 -->|"activates"| ZBTB20
GENES -->|"activates"| ZBTB20
CD8["CD8"] -->|"target for"| ZBTB20
SPP1["SPP1"] -->|"target for"| ZBTB20| Target | Relation | Type | Str |
|---|---|---|---|
| Cancer | associated_with | disease | 0.65 |
| Tumor | associated_with | disease | 0.65 |
| Cancer | therapeutic_target | disease | 0.65 |
| Tumor | therapeutic_target | disease | 0.65 |
| ETV6 | activates | gene | 0.60 |
| CAMK4 | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| stroke | regulates | disease | 0.60 |
| mitochondrial function | participates_in | pathway | 0.60 |
| T Cell | associated_with | cell_type | 0.60 |
| CD8 | associated_with | gene | 0.60 |
| ANK3 | activates | gene | 0.60 |
| SPP1 | associated_with | gene | 0.60 |
| GENES | activates | gene | 0.60 |
| CANCER | associated_with | gene | 0.60 |
| RNA | associated_with | gene | 0.60 |
| TEX | expressed_in | cell_type | 0.56 |
| T Cell | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ZBTB20 in their description or question text
No additional research found