concept

ALOXE3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ALOXE3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

55Connections

0Hypotheses

0Analyses

31Outgoing

24Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ALOXE3
Key Genes/Proteins	ALOX, ALOX12, ALOX12B, ALOX15, ALOX15B, ALOX5
Related Diseases	Als, ALS, Cancer

Pathway Diagram

graph TD
    ALOXE3["ALOXE3"]
    ALOXE3 -->|"interacts"| Als["Als"]
    ALOXE3 -->|"activates"| Cancer["Cancer"]
    ALOXE3 -->|"interacts"| ALS["ALS"]
    ALOXE3 -->|"contributes to"| ALOX12["ALOX12"]
    ALOXE3 -->|"contributes to"| AND["AND"]
    ALOXE3 -->|"contributes to"| ALOX15B["ALOX15B"]
    ALOXE3 -->|"contributes to"| ALOX["ALOX"]
    GENES["GENES"] -->|"contributes to"| ALOXE3
    ALOX12B["ALOX12B"] -->|"contributes to"| ALOXE3
    ALOX5["ALOX5"] -->|"contributes to"| ALOXE3
    ALOX15["ALOX15"] -->|"contributes to"| ALOXE3
    CANCER["CANCER"] -->|"activates"| ALOXE3

Outgoing (31)

Target	Relation	Type	Str
Lipoxygenases	associated_with	enzyme	0.90
ALOX15	associated_with	gene	0.85
lipoxygenase	associated_with	enzyme	0.80
Cancer	activates	disease	0.65
Als	interacts_with	disease	0.65
ALS	interacts_with	disease	0.65
ALOX12B	contributes_to	gene	0.60
ALOX5	contributes_to	gene	0.60
ferroptosis	participates_in	pathway	0.60
AND	contributes_to	gene	0.60
AND	activates	gene	0.60
App	interacts_with	protein	0.60
Ras	activates	protein	0.60
ALOX	contributes_to	gene	0.60
ferroptosis	activates	process	0.60
ALOX12	activates	gene	0.60
FER	activates	gene	0.60
HMOX1	activates	gene	0.60
NFE2L2	activates	gene	0.60
CHAC1	activates	gene	0.60
ALOX12	contributes_to	gene	0.60
Ferroptosis	activates	pathway	0.60
GSH	activates	gene	0.60
FERROPTOSIS	activates	gene	0.60
ALOX5	activates	gene	0.60
GENES	contributes_to	gene	0.60
SAT1	activates	gene	0.60
RNA	activates	gene	0.60
GENES	activates	gene	0.60
ALOX15B	contributes_to	gene	0.60
ALOX15	activates	gene	0.60

Incoming (24)

Source	Relation	Type	Str
ALOX15	associated_with	gene	0.80
ALOX12B	contributes_to	gene	0.60
ALOX5	contributes_to	gene	0.60
GENES	activates	gene	0.60
ALOX5	activates	gene	0.60
ALOX15	activates	gene	0.60
CANCER	activates	gene	0.60
GENES	contributes_to	gene	0.60
ALOX	implicated_in	gene	0.60
ALOX12	implicated_in	gene	0.60
ALOX12B	implicated_in	gene	0.60
ALOX15B	implicated_in	gene	0.60
ALOX5	implicated_in	gene	0.60
FERROPTOSIS	activates	gene	0.60
ALOX15B	contributes_to	gene	0.60
ALOX12	contributes_to	gene	0.60
HMOX1	activates	gene	0.60
RNA	activates	gene	0.60
NFE2L2	activates	gene	0.60
ALOX	contributes_to	gene	0.60
SAT1	activates	gene	0.60
ALOX12	activates	gene	0.60
GSH	activates	gene	0.60
CHAC1	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ALOXE3 in their description or question text

No additional research found