protein

RBFOX2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RBFOX2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

33Connections

0Hypotheses

0Analyses

20Outgoing

13Incoming

0Experiments

0Debates

Summary

Page for RBFOX2 Protein

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🔬 Protein Info

Gene Symbol	RBFOX2
Full Name	RNA Binding Fox-1 Homolog 2 (RBFOX2)
Chromosome	22q12.3
Protein Type	Gene
Function	It plays critical roles in
Molecular Weight	44.5 kDa
Amino Acids	90 aa
Pathways	Amyloid
UniProt ID	Q9BQY4
NCBI Gene ID	61643
Ensembl ID	ENSG00000100320
GeneCards	RBFOX2
Human Protein Atlas	RBFOX2
Associated Diseases	Amyotrophic Lateral Sclerosis (ALS), Parkinson's Disease, Cancer, Epilepsy, Autism Spectrum Disorder
Interactions	CANCER, HNRNPM
KG Connections	33 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RBFOX2 — AlphaFold Q9BQY4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

RNA Binding Fox-1 Homolog 2 (RBFOX2)

gene · 1325 words

→

RBFOX2 Protein

protein · 1169 words

→

Pathway Diagram

graph TD
    RBFOX2["RBFOX2"]
    Cancer{"Cancer"}
    RBFOX2 -->|"interacts with"| Cancer
    Tumor{"Tumor"}
    RBFOX2 -->|"regulates"| Tumor
    RAC1["RAC1"]
    RBFOX2 -->|"expressed in"| RAC1
    MYC["MYC"]
    RBFOX2 -->|"regulates"| MYC
    CANCER["CANCER"]
    RBFOX2 -->|"interacts with"| CANCER
    HNRNPM["HNRNPM"]
    RBFOX2 -->|"interacts with"| HNRNPM
    neurodegeneration["neurodegeneration"]
    RBFOX2 -->|"implicated in"| neurodegeneration
    style RBFOX2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (20)

Target	Relation	Type	Str
Cancer	interacts_with	disease	0.65
Tumor	regulates	disease	0.65
Alzheimer	regulates	disease	0.65
ALZHEIMER	regulates	gene	0.60
RNA	regulates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
AMYLOID	regulates	gene	0.60
Amyloid	regulates	pathway	0.60
HNRNPM	interacts_with	gene	0.60
Nfkb	regulates	protein	0.60
RAC1	expressed_in	gene	0.60
CANCER	interacts_with	gene	0.60
Rb	expressed_in	protein	0.60
MYC	regulates	gene	0.60
hippocampus	expressed_in	brain_region	0.60
TAU	regulates	gene	0.60
MEF2C	expressed_in	gene	0.60
GUCY1B1	expressed_in	gene	0.60
Cortex	expressed_in	brain_region	0.55
Cerebellum	expressed_in	brain_region	0.55

Incoming (13)

Source	Relation	Type	Str
TAU	regulates	gene	0.60
GENETIC RISK LOCI	regulates	gene	0.60
NFKBIA	regulates	gene	0.60
GUCY1B1	expressed_in	gene	0.60
MEF2C	expressed_in	gene	0.60
MEF2C	associated_with	gene	0.50
GUCY1B1	associated_with	gene	0.50
GUCY1B1	co_discussed	gene	0.50
MEF2C	co_discussed	gene	0.50
NFKBIA	co_discussed	gene	0.50
ALZHEIMER	regulates	gene	0.50
AMYLOID	regulates	gene	0.50
RNA	regulates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RBFOX2 in their description or question text

No additional research found