gene

FUBP1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FUBP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

55Connections

0Hypotheses

0Analyses

38Outgoing

17Incoming

0Experiments

0Debates

Summary

FUBP1 is a gene implicated in neurodegeneration research. Key relationships include: associated with, implicated in, biomarker for. Associated with AD, Breast Cancer, Cancer. Connected to 40 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	FUBP1
Full Name	Far Upstream Element Binding Protein 1
Chromosome	1p31.1
Function	is a multifunctional DNA and RNA-binding protein that plays critical roles in transcriptional regulation, RNA processing, and the DNA damage response.
Amino Acids	650 aa
Pathways	Consequence
UniProt ID	Q96AE4
NCBI Gene ID	2260
Ensembl ID	ENSG00000107223
OMIM	608470
GeneCards	FUBP1
Human Protein Atlas	FUBP1
Associated Diseases	AD, cancer, glioma, Ms, pilocytic astrocytoma, RA
Interactions	CANCER, MYC, USF2
KG Connections	55 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: FUBP1 — AlphaFold Q96AE4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

FUBP1 Gene

gene · 1106 words

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Pathway Diagram

graph TD
    FUBP1["FUBP1"]
    Cancer{"Cancer"}
    FUBP1 -->|"biomarker for"| Cancer
    Neurodegeneration{"Neurodegeneration"}
    FUBP1 -->|"biomarker for"| Neurodegeneration
    Ms{"Ms"}
    FUBP1 -->|"biomarker for"| Ms
    Glioma{"Glioma"}
    FUBP1 -->|"biomarker for"| Glioma
    H3F3A["H3F3A"]
    FUBP1 -->|"associated with"| H3F3A
    OVERVIEW["OVERVIEW"]
    FUBP1 -->|"biomarker for"| OVERVIEW
    BRAF["BRAF"]
    FUBP1 -->|"associated with"| BRAF
    ATRX["ATRX"]
    FUBP1 -->|"associated with"| ATRX
    JUN["JUN"]
    FUBP1 -->|"biomarker for"| JUN
    IDH1["IDH1"]
    FUBP1 -->|"associated with"| IDH1
    CIC["CIC"]
    FUBP1 -->|"associated with"| CIC
    TERT["TERT"]
    FUBP1 -->|"associated with"| TERT
    IDH1 -->|"associated with"| FUBP1
    TERT -->|"associated with"| FUBP1
    JUN -->|"biomarker for"| FUBP1
    CIC -->|"associated with"| FUBP1
    BRAF -->|"associated with"| FUBP1
    ATRX -->|"associated with"| FUBP1
    OVERVIEW -->|"biomarker for"| FUBP1
    AND["AND"]
    AND -->|"associated with"| FUBP1
    CANCER["CANCER"]
    CANCER -->|"biomarker for"| FUBP1
    H3F3A -->|"associated with"| FUBP1
    style FUBP1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (38)

Target	Relation	Type	Str
BRAIN TUMOURS	associated_with	entity	0.85
Ms	biomarker_for	disease	0.65
Neurodegeneration	biomarker_for	disease	0.65
Tumor	interacts_with	disease	0.65
Breast Cancer	activates	disease	0.65
Cancer	activates	disease	0.65
Glioma	biomarker_for	disease	0.65
Cancer	biomarker_for	disease	0.65
BRAF	associated_with	gene	0.60
NEURODEGENERATION	biomarker_for	gene	0.60
H3F3A	biomarker_for	gene	0.60
BRAF	biomarker_for	gene	0.60
CIC	biomarker_for	gene	0.60
ATRX	biomarker_for	gene	0.60
ATRX	associated_with	gene	0.60
CANCER	biomarker_for	gene	0.60
CANCER	activates	gene	0.60
Metastasis	implicated_in	pathway	0.60
Invasion	implicated_in	pathway	0.60
H3F3A	associated_with	gene	0.60
OVERVIEW	biomarker_for	gene	0.60
Fus	associated_with	protein	0.60
App	biomarker_for	protein	0.60
MYC	activates	gene	0.60
IDH1	biomarker_for	gene	0.60
TERT	biomarker_for	gene	0.60
Raf	associated_with	protein	0.60
JUN	biomarker_for	gene	0.60
IDH1	associated_with	gene	0.60
CIC	associated_with	gene	0.60
TERT	associated_with	gene	0.60
AD	implicated_in	disease	0.50
Ms	implicated_in	disease	0.50
RA	implicated_in	disease	0.50
SS	implicated_in	disease	0.50
pilocytic astrocytoma	implicated_in	disease	0.50
glioma	implicated_in	disease	0.50
cancer	implicated_in	disease	0.50

Incoming (17)

Source	Relation	Type	Str
NEURODEGENERATION	biomarker_for	gene	0.60
AND	associated_with	gene	0.60
IDH1	associated_with	gene	0.60
TERT	associated_with	gene	0.60
JUN	biomarker_for	gene	0.60
CIC	associated_with	gene	0.60
ATRX	associated_with	gene	0.60
TERT	biomarker_for	gene	0.60
ATRX	biomarker_for	gene	0.60
BRAF	biomarker_for	gene	0.60
CIC	biomarker_for	gene	0.60
CANCER	biomarker_for	gene	0.60
BRAF	associated_with	gene	0.60
OVERVIEW	biomarker_for	gene	0.60
H3F3A	associated_with	gene	0.60
GAIN	implicated_in	gene	0.60
USF2	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FUBP1 in their description or question text

No additional research found