concept

BTG2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BTG2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

83Connections

0Hypotheses

0Analyses

47Outgoing

36Incoming

0Experiments

0Debates

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💡 Concept Info

Name	BTG2
Key Genes/Proteins	ACTB, ALS, AMYOTROPHIC LATERAL SCLEROSIS, AND, APOE, App
Related Diseases	Als, Amyotrophic Lateral Sclerosis, cancer, Cancer

Pathway Diagram

graph TD
    BTG2["BTG2"]
    BTG2 -.biomarker for.-> Gastric_Cancer["Gastric Cancer"]
    BTG2 -->|"inhibits"| Cancer["Cancer"]
    BTG2 -->|"causes"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    BTG2 -->|"causes"| Als["Als"]
    BTG2 -->|"causes"| Neurodegeneration["Neurodegeneration"]
    BTG2 -->|"inhibits"| PRMT1["PRMT1"]
    BTG2 -->|"inhibits"| GENES["GENES"]
    AKT["AKT"] -->|"inhibits"| BTG2
    PRMT1 -->|"interacts"| BTG2
    GENES -->|"inhibits"| BTG2
    NEURODEGENERATION["NEURODEGENERATION"] -->|"causes"| BTG2
    OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"causes"| BTG2
    IL1B["IL1B"] -->|"causes"| BTG2
    SOD1["SOD1"] -->|"regulates"| BTG2
    IL6["IL6"] -->|"causes"| BTG2
    TP53["TP53"] -->|"causes"| BTG2

Outgoing (47)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:BTG2	data_in	dataset_row	0.00
Antitumor Effects	mediates	process	0.80
Gastric Cancer	associated_with	disease	0.80
Gastric Cancer	biomarker_for	disease	0.75
tumor growth	suppresses	process	0.75
ubiquitin-proteasome	participates_in	pathway	0.70
Neurodegeneration	regulates	disease	0.65
Als	regulates	disease	0.65
Amyotrophic Lateral Sclerosis	regulates	disease	0.65
Cancer	inhibits	disease	0.65
Tumor	associated_with	disease	0.65
Neurodegeneration	causes	disease	0.65
Amyotrophic Lateral Sclerosis	causes	disease	0.65
Als	causes	disease	0.65
Ms	inhibits	disease	0.65
CASP3	causes	gene	0.60
NFE2L2	regulates	gene	0.60
VEGFA	causes	gene	0.60
CNR1	regulates	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	causes	gene	0.60
APOE	causes	gene	0.60
Oxidative Stress	causes	pathway	0.60
Mapk	regulates	pathway	0.60
Epigenetic	therapeutic_target	pathway	0.60
EGR1	associated_with	gene	0.60
PRMT1	inhibits	gene	0.60
EGR1	encodes	gene	0.60
GENES	inhibits	gene	0.60
CANCER	inhibits	gene	0.60
Epigenetic	inhibits	pathway	0.60
ALS	causes	gene	0.60
NRF2	causes	gene	0.60
APP	causes	gene	0.60
SOD1	regulates	gene	0.60
OXIDATIVE STRESS	causes	gene	0.60
Sod1	regulates	pathway	0.60
NEURODEGENERATION	causes	gene	0.60
AND	regulates	gene	0.60
CASP3	regulates	gene	0.60
MAPK	regulates	gene	0.60
SNCA	regulates	gene	0.60
App	therapeutic_target	protein	0.60
Oxidative Stress	regulates	pathway	0.60
PRMT1	associated_with	gene	0.60
MAPK signaling	participates_in	pathway	0.60
AMYOTROPHIC LATERAL SCLEROSIS	regulates	gene	0.60
APOE	regulates	gene	0.60

Incoming (36)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:BTG2	data_in	dataset_row	0.00
PRMT1	regulates	entity	0.85
PRMT1	associated_with	gene	0.80
AKT	inhibits	gene	0.80
PRMT1	interacts_with	gene	0.80
MAPK	regulates	gene	0.60
ALS	causes	gene	0.60
EGR1	associated_with	gene	0.60
AND	inhibits	gene	0.60
GENES	therapeutic_target	gene	0.60
CANCER	inhibits	gene	0.60
GENES	inhibits	gene	0.60
PRMT1	inhibits	gene	0.60
NEURODEGENERATION	causes	gene	0.60
OXIDATIVE STRESS	causes	gene	0.60
IL1B	causes	gene	0.60
SOD1	regulates	gene	0.60
IL6	causes	gene	0.60
TP53	causes	gene	0.60
ACTB	causes	gene	0.60
SNCA	regulates	gene	0.60
ALS	regulates	gene	0.60
NEURODEGENERATION	regulates	gene	0.60
CNR1	regulates	gene	0.60
IL1B	regulates	gene	0.60
IL6	regulates	gene	0.60
TP53	regulates	gene	0.60
VEGFA	regulates	gene	0.60
ACTB	regulates	gene	0.60
OXIDATIVE STRESS	regulates	gene	0.60
NRF2	regulates	gene	0.60
APP	regulates	gene	0.60
cancer	inhibits	disease	0.50
Gastric Cancer	inhibits	disease	0.50
Sod1	regulates	gene	0.50
NFE2L2	regulates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning BTG2 in their description or question text

No additional research found