Closed-loop tACS targeting EC-II SST interneurons to block tau propagation and restore perforant-path gamma gating in AD
h-var-3b982ec3d2
## Mechanistic Overview
Closed-loop tACS targeting EC-II SST interneurons to block tau propagation and restore perforant-path gamma gating in AD starts from the claim that modulating SST within the disease context of Alzheimer's disease can redirect a disease-relevant process. The original description reads: "## Mechanistic Overview Closed-loop tACS targeting EC-II SST interneurons to block tau pr
Elo ratings (across arenas)
| Arena | Rating | RD | W-L-D | N |
|---|---|---|---|---|
| alzheimers | 2005 | ±72 | 38-16-0 | 54 |
| loop:loop-74f20cb27aad | 1764 | ±209 | 3-0-2 | 5 |
| global | 1707 | ±127 | 8-5-0 | 13 |
| tournament:top50 | 1418 | ±186 | 1-3-0 | 4 |
Ancestry (oldest → this)
mutate · gen 1
parent: h-bdbd2120
mutate · gen 2
parent: h-var-d749cd28cb
Descendants
1404 (6 matches)
1823 (52 matches)
1883 (53 matches)
2127 (55 matches)
1630 (44 matches)
1319 (4 matches)
1208 (2 matches)
1208 (2 matches)
1515 (8 matches)
1449 (11 matches)
1228 (3 matches)
1701 (24 matches)
1613 (16 matches)
1547 (16 matches)
1500 (0 matches)
1500 (0 matches)