Closed-loop tACS targeting EC-II PV interneurons to enhance perisomatic inhibition and block tau propagation in AD
h-var-9da3ee8550
## Mechanistic Overview
Closed-loop tACS targeting EC-II PV interneurons to enhance perisomatic inhibition and block tau propagation in AD starts from the claim that modulating PVALB within the disease context of Alzheimer's disease can redirect a disease-relevant process. The original description reads: "## Mechanistic Overview Closed-loop tACS targeting EC-II PV interneurons to enhance perisomat
Elo ratings (across arenas)
| Arena | Rating | RD | W-L-D | N |
|---|---|---|---|---|
| alzheimers | 1319 | ±222 | 0-4-0 | 4 |
Ancestry (oldest → this)
mutate · gen 1
parent: h-bdbd2120
mutate · gen 2
parent: h-var-d749cd28cb
mutate · gen 3
parent: h-var-3b982ec3d2
Descendants
(no variants yet)