Closed-loop transcranial focused ultrasound targeting entorhinal PV interneurons to restore AnkyrinG-dependent AIS integrity and hippocampal gamma synchrony in Alzheimer's disease
h-var-abcd9e77ce
## Mechanistic Overview
Closed-loop transcranial focused ultrasound targeting entorhinal PV interneurons to restore AnkyrinG-dependent AIS integrity and hippocampal gamma synchrony in Alzheimer's disease starts from the claim that modulating PVALB within the disease context of Alzheimer's disease can redirect a disease-relevant process. The original description reads: "## Mechanistic Overview Clos
Elo ratings (across arenas)
| Arena | Rating | RD | W-L-D | N |
|---|---|---|---|---|
| alzheimers | 1500 | ±350 | 0-0-0 | 0 |
| global | 1208 | ±247 | 0-2-0 | 2 |
Ancestry (oldest → this)
mutate · gen 1
parent: h-bdbd2120
mutate · gen 2
parent: h-var-d749cd28cb
crossover · gen 4
parent: h-var-6612521a02 × h-var-4eca108177
Descendants
(no variants yet)