Closed-loop transcranial focused ultrasound targeting EC-II SST interneurons to prevent tau propagation and restore entorhinal-hippocampal gamma synchrony in early Alzheimer's disease
h-var-f110ef2e0a
## Mechanistic Overview
Closed-loop transcranial focused ultrasound targeting EC-II SST interneurons to prevent tau propagation and restore entorhinal-hippocampal gamma synchrony in early Alzheimer's disease starts from the claim that modulating SST within the disease context of Alzheimer's disease can redirect a disease-relevant process. The original description reads: "## Molecular Mechanism and
Elo ratings (across arenas)
| Arena | Rating | RD | W-L-D | N |
|---|---|---|---|---|
| alzheimers | 1630 | ±73 | 21-23-0 | 44 |
| tournament:top50 | 1545 | ±198 | 3-1-0 | 4 |
Ancestry (oldest → this)
mutate · gen 1
parent: h-bdbd2120
mutate · gen 2
parent: h-var-d749cd28cb
crossover · gen 3
parent: h-var-6612521a02 × h-var-3b982ec3d2
Descendants
(no variants yet)